I commute in my 91 with 255/85/r16s most days. It's got the crappy 2.8 V6 and a manual trans, and gets about 15 mpg mixed city/hwy. I have some new R&P gears to put in, but I don't know if they'll make much of a difference...
Comfort has been OK. I am running OME springs and shocks (they're great). I had some cheap shocks and stock springs before, and it sucked.
I start feeling cramped after about 2-3 hours in it and want to get out and stretch, but it's fairly comfortable for something designed in the 80's!
Disclaimer: I have always driven old/modified vehicles, and usually put ~10k miles/year on motorcycles, so my expectations for comfort may be lower than the average person :xxrotflma