I am planning a rear heater or two using engine coolant for BigB...
My 35' Airstream has one in addition to the 2 propane furnaces, and it works well. Many Vans came with one from the factory, so easy to find at the junkyard if you dont have one. If you do, then just the simple use of distilled water/ antifreeze and replace older hoses like you should do for your engine will keep things reliable.
A couple of points...
A supply of hot coolant from the engine is free... and a good propane furnace or other system is not... in fact a calorifier can cost $2000 or more.
If installing a new system I suggest..
Coolant supply should come from a manual bypass valve installed on the original heater supply pipe. That way when the engine is running the larger rear area gets the hot coolant first, allowing a faster warm up. Also it will give you the option to turn of the system when not needed or if you do have a leak!
Use hard pipes for the long runs. They should be protected, insulated and supported correctly. Also minimise the flexible hoses in the system, and use Silicon that is longer lived.
People sitting in the rear of you van will enjoy the benefit of a coolant based heating system and maybe they can control the fan output to keep them cozy.
Remember, you should not use a propane system when traveling...
An additional benefit and an old trick will be the option to switch on the system in extreme climbs or traffic on hot days... the will add a huge amount of coolant and heat dissapatiion capacity to you cooling system and most of the time, save you from an overheat situation.
I do this on my Airstream and you would be surprised how much difference it made... On a 90f day recently I blasted up and over the continental divide in NM... 9000'+ and my BBC started to get warmer, and close to the 220F mark pulling the 16500lb beast up in 2nd gear at 30mph.. I put on the heater and opened a window or two... and the temp came down to the normal 200F and stayed down..
Dont dismiss the simplicity, costs and benefits!