Honestly Treadrights have been the best tire I've ever had on my 3/4 ton work truck (7200 lbs daily including the metal contractor cap and tools). My daily driving style in rural Pennsylvania is very similar to the imagined use of many overlanders- 80% road/20% dirt.
My first set was the BFG style tread and they performed great. All four tires lasted 35k miles when the best mileage I ever got out a set of tires was 25k (stick shift and a v10 are hard on tires). I bought different wheels and tires after the first set wore out, but I kept the Treadrights for spares and to use on my M116a2 military trailer that gets used for all kinds of general hauling, loaded up to 2 tons, on and off road. They were fine until dry rot started breaking down the sidewalls like what would happen with any tire.
Now I'm on my second set. My off road use is actually a bit more frequent and more difficult when I do, so I figured I'd try the mud terrain tire that is based on the Goodyear MTR tread. I also splurged for the Kedgegrip . They delivered in 3 days, much quicker than I expected. I had the shop do a static balance like Treadright recommends and the ride is quite smooth, with no balance issues, minimal weights were required, and to put the cherry on top, it was cheaper than a standard balance. Even my 83 year old grandfather comments on how well my "big ol' tires" ride on the road. The wife likes that she has yet to actually put the truck into 4wd this winter, and I'm actually a bit disappointed because I do enjoy the little bit of drama of controlled-snow-day drifting.
I recommended Treadrights to my brother for his Power Wagon and he loved them. He had one tire go out of balance on highway trip after 5k miles of use, and the company replaced it at no cost after emailing the pictures of the tire.
When my brother had his tires installed on his Power Wagon, he had balance issues until he went back and had them static balanced. After that he had no problems. He kept his tires (D rated 35s) until he bought a 37' long 5th wheel toyhauler and his truck was loaded at at max capacity. We sold his Treadrights to a guy who is now happily using them on his diesel-powered Ford Expedition that is his wife's daily driver, and they haven't had any issues of which we are aware.
Tips I'd give are 1) keep your receipts for warranty issues, 2) static balance tires per Treadright recommendation, 3) rotate on a regular schedule, and 4) these are the only tires I've EVER purchased that actually measure as what dimensions they are sold. A 35" Treadright tire is 35" tall. Like lumber, most manufacturers sell tires that are a bit smaller than what they advertise, so the size that fit on your truck before may be a tighter fit with Treadrights.
Overall, I'm a happy customer, and I recommend them to others.