If it's a good seller it might prompt other manufacturers to come up with something similar. The car-based-pickup concept has been tried several times since the demise of the El Camino and Ranchero, with only limited success: The Dodge Rampage in the mid 80's, the VW pickup a couple of years later, into the early 90's I believe, and the Subaru Baja. All were dropped from the US market after dismal sales but it's worth noting that most of them were introduced at a time when compact "mini-trucks" (we'd call them "mid-sized trucks" now) were flourishing. Also all were introduced at a time when gas prices were low, which meant that their high MPG numbers were not much of a selling point.
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Even though gas is priced low now, I don't expect that to last. I have to say I kind of like this more than the odd "Mini Avalanche" styling of the previous gen. This one looks like an actual pickup.
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Still disappointed that they didn't include a disappearing mid-gate like the Avalanche, I always thought that was a brilliant solution to the cargo - vs - passengers problem with extended cab trucks (the problem, in a nutshell, is this: If you provide enough space for passengers, then you either end up with a too-short bed, or with a vehicle that has a too-long wheelbase. The Avalanche solved that problem by having an area that could be used for either one, just by removing the mid-gate and flipping the seats up.)
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Of course, some might say "if the Avalanche was such a good idea why did Chevy drop it?" My understanding is that it was not due to poor sales, but because Chevy figured the same customers for the Avalanche would buy a 4 door Silverado instead. Since the Silverado has a simpler suspension (leafs vs. 4-link and coils) and does not have the single body with the disappearing mid-gate, it's cheaper to produce.
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I think this is actually the direction that "compact" or "mid sized" pickups will eventually evolve towards. We might

at a car-based unibody "pickup" but for most users, especially those in urban/suburban areas, this is about all the "truck" they need.