More is better and it's likely if you're less than even a few wavelengths the receiving radio will be overloaded and unable to hear anything while the other is transmitting. That's called desense, short for desensitizing the radio. Where exactly this goes from annoying to damaging isn't cut and dry.
If your radio is exposed to a very strong local field long enough it'll probably ruin it eventually. Key part is "eventually". Very close (like an inch) that might be a handful of exposures even at low power. Go out to a foot, 5 feet, 15 feet the time it takes goes up exponentially until it's essentially never going to damage anything even at 50 or 100 watts.
So my rule of thumb (which is worth a cup of coffee at best) is (1) NEVER let antenna whips touch and (b) try to stay one wavelength apart on the lowest band of interest (e.g. 2 meters apart if you're looking at two 2m ham radios).
Rule (b) is subjective because it's impossible below 2m to achieve this on a vehicle and even 2m mobile is a tough one. So just do your best and remember the rule to use the lowest power you can.
Rule (1) should never be ignored, especially with metal whips. If you short a transmitting radio antenna to another radio you'll almost certainly ruin one or both quickly. Maybe not once or twice but it's not something you want to do very often.
BTW, should mention that when dealing with 2m VHF you should also consider it's location relative to your vehicle commercial AM/FM radio. At 50W a 2m ham radio can upset 88-108 FM radios pretty badly. Also think about GPS antennas and devices and things like Sirius/XM or InReach/SPOT. Those devices operate in a much higher range of frequencies but they have extremely sensitive RF front ends that could be easily damaged, not to mention practical issues like throwing off your navigation. They need a clear line of sight to the sky free of interference and a couple of feet of separation can't hurt.