Man, i'd work out a bathroom if at all possible. I think you'll thank me later. I've had rigs with and without and I'm currently building a smallish pop top van for the two of us now that kids are older that has only a porta potty and an outdoor shower, BUT, we've been traveling all 50 states since our kids were born and we know our limitations and desires. We like to hit a motel, truck stop or the like for a shower every few days if the weather isn't perfect and don't worry about the cost.
There are a million ways to do it and only one absolute truth. Most women prefer a proper bathroom.