I think that would depend on if the trailer is wider than the tow vehicle.. if not then it would draft alot better behind the TV w/the leading edge lower than the TV roofline.. If the trailer was wider than the tow vehicle, a V-Nose would probably be the better of the two.
Aero is nice, but really only at interstate speeds.. I'd venture that most are like my self and attempt stay off the interstates intentionally, unless I really need to cover alot of ground quickly aero is not that big of a concern, especially as your setup gets heavier/bigger and driving it full out on interstates for long distances gets requires exponentially more fuel/money.
I've towed alot with cars because a little cargo trailer drafting behind the vehicle got significantly better fuel economy than strapping on a roof rocket or something for more cargo room.. but that was almost strictly an interstate setup, I had to cover a few thousand miles in very little time regularly.