I bought the DC Extreme Country 255/85-16, load range E. They replaced Duratrac 245/75-16 (load range C), and I was concerned about the ride quality going to E on my relatively light 4runner. I haven't really noticed them being significantly stiffer or harsher than the "C" Duratracs that preceded them. A lot more tread noise for sure, and a big change in torque to the road with the larger diameter.
So far I've been using similar pressures to what I used on the Duratracs: 35psi on the road, 22-25 psi on dirt roads (based on wear measurements, I might need to decrease my road pressure.) I haven't been on anything that required lower pressures, although I have been on several difficult roads where lower pressure would've helped quite a bit. Guess I was too lazy to let out more air.
I'm not impressed with the wear, which was ~0.1" in 4200 miles. Those were either highway miles, or dirt miles, since I only use the 4runner on trips.
At this wear rate, I'm already thinking about my next set of tires. Maybe the Cooper ST Maxx is in my future, unless there are Duratrac or General Grabber X3 offered in this size next time around. The Duratracs were awesome tires for my needs, just too small.