I used dow 25 psi blue foam, I have 2 skins made of fiber glass sheet. Its plenty strong, people have been using this style to build things for 60 or so years.
Styromax builds 30 foot campers from 25 psi foam, mine and Jess's are both 25 psi foam. My trailer has about 5k miles with no issues. I would not use polyiso, and would have loved to be able to afford polyurethane foam. There are refer trucks driving around this country made with foam panels skined with fiberglass that probably have a million miles on em.
Once something is built, its not some much the bonding of the skins to the foam, it is the compressibility of the foam. The way the skins and foam get put under compression and tension does not need a super bond. it spread out over the whole panel. A 4x8 panel has 4608 square inches, so even if 1/2 the panel is not seeing any stress it can still support a ton and only have a 1 psi load.
I guess all those boats with balsa wood and foam cores that sail around the world for the 50 years are going to fail any day now.