I was looking for a Ford van as well because I wanted the V10 and the frame was thought to be stronger.
I got a 02 chevy 3/4 ton conversion van with Quigley 4x4 with independent front suspension. I have exact same use as OP - it's my ultimate road trip vehicle. For towing boat on trips and road trips with family. It has a 350 5.7L motor. It's been good to me so far and rides great. My frame was reinforced by Quigley so no worries there.
Somethings you need to know. The louder noise on fords is a result of ford not using any noise pads whereas they come stock on chevy's. Fords have a better departure and arrival angle, which makes it more offroad capable. I've heard the Fords can tow more, but the GVWR on newer gassers are not any different. It's the Ford diesels that are supposed to tow a lot more. I think chevy drivetrain is better, but you really need a 3/4 ton if your going to tow a boat or the transmission could be suspect IMO, especially on a higher mileage buy. The 3/4 ton and up GM transmissions are near bullet proof from what I've read. I can say that at 155K miles mine still feels very solid.
I recommend OP find a conversion van instead of modifying a passenger van. You can do same modifications on conversion van, but there will be much less work to do it. You will get a bed that folds down and likely TV. Most middle seats have captain chairs on quick release mounts so it's just a matter of removing one seat and adding your Microwave or whatever you want there.