I’ve ridden mountain bikes for years, motos off and on over the years, and driven quite a few vehicles. With Mountain bikes it was always a balance between pedaling the lightest tire you can that was dependable. In the end, with all forms of locomotion, I always ended up at the beefier side due to durability issues. My MTB tires used to weight in the mid 500 grams, and now are over 1000 grams. They are dead nuts dependable, and I can hit it hard without then holding me back. They suck to accelerate though. Having said that tire punctures suck, plain and sImple. They are inconvenient at best, and catastrophic at worst. Think 75 mph on the highway with a high profile vehicle carrying a lot of weight (you’re driving an F350 after all), a tall side wall, and a blow out. BTW I have 255/85R16 E’s on my hundred series. Switched from 285/75 and never looked back. So I agree with you that narrow has benefits. 1” difference in width isn’t that much of a difference when talking about a 37” tire. My vote is durability in this case. Nothing is puncture proof, or fool proof, but like to stack the deck in my favor as much as possible. YMMV