Bear Spray will definitely be purchased but I would also feel a little safer with a firearm.
Something large like a rifle or shotgun is out of the question as I plan to keep my gun in secured tuffy box inside my Fj and need to easily store it at home. So I should be looking at a 10mm? Everywhere I look online most guns that fall within my budget are S&W, some Rugers, and other random brands. Is S&W my best bet?
You're going to get all kinds of brand loyalists stirred up with that kind of question.
If you're truck-based, I don't see why a shotgun or rifle is out of the question; the weight and size shouldn't be an issue and you can use an action lock or locked case if you're that worried about the firearm's safety. Hands-down, either of those are much better for dealing with big critters than a pistol; they are both easier to aim and throw much bigger projectiles (on average) at much higher velocities. When people talk about carrying a pistol for bear defense, they're almost always doing so because they weren't able to carry a shotgun or rifle; a pistol is very much a compromise weapon for, well, any sort of self-defense situation.
That said, if you're absolutely dead-set against a rifle or shotgun, go buy a pistol in a caliber that you feel comfortable shooting; the odds of you having to shoot a bear are slim to none. But you should be capable of making consistent shots; if you're going to jerk your shots because you're anticipating the recoil (with something like a 10mm) you'll just miss. Bear spray will be easier to deploy, though it's not foolproof.
And to be honest, unless you're going into some remote part of Canada or Alaska, bear spray, a buddy or two, and some common sense should be all the tools you need to deal with any bear threats.