For those of us with small kids, who are now walking...
I went to wal-mart and picked up a nice retractable 15 foot long dog leash and it has been great. I strap it around my son's mid section, or belt line, either way, and he can get around and play plenty, but I do not have to pay a ton of attention to him while I am working on something. Other than that I can stick him in the jeep for a little while to play while I am doing things as well.
My wife and I picked up a nice little pop up tent trailer, and that has been amazing for us. We can get the kids down inside, and still have time for one another. Plus if your spouse is not so into camping, a real bed, real dinner table, and a sink and stove to cook on are a big plus.
Our trailer did not come with a toilet in it (nor the stove come to that) the PO kept both for some odd reason. So I went to home depot and bought a little orange five gallon bucket, and then I got a seat that was made to snap onto the bucket, with bags that line the thing. It works great, instant toilet and it only cost me about ten bucks. Grab the bag in the morning, toss in the baby's diaper, and find a trash can to put it in!
Last thing, we end up having to stop some more than my wife and I would like, but we get the kids running around a bit, and it helps a lot. We also have a nice movie system that we can hang on the back of our chairs for the boys to watch. This type is better than the built in set up because you can also take it inside the trailer and the kids can watch a short or something while they are getting ready/ winding down for bed.
Well, that is how it works for me. Don't be afraid to take the kids out by yourself Dad, you can do it.
Pleasant travels!