The one word of advice I will offer on traveling in Mexico, if you are anything like me - and I suspect you might be - little out-of-the-way places are where 99% of the charm is...
For instance, there is a hot springs at Aconchi, Sonora that is so far out in the middle of nowhere that I had to ask passing cowboys (yes, real cowboys on horseback... really working livestock) if I had missed the turn... they laughed and told me to keep going! When we got there, we were the only gringos around. The small crowd of locals were having a picnic (there is ALWAYS a reason to have a family picnic...you see them often) and invited my wife and I to join them for the BBQ and beer. We ate, drank and laughed until the evening wore on. My Spanish is passable, my wife's is slightly better, but it didn't much matter. We spoke the international language of the pleasant experience. Sitting under the live oak trees, beside the fire, eating real Mexican BBQ, quaffing a Dos Equis, listening to the sounds of the children playing, the music, the laughter, smell of the desert going to sleep.
You cannot buy that experience anywhere. It just happens.
In Mexico, it happens often.