Nomenclature in this thread seems to be sideways too.
Tall gears, AKA high gears = low numerical gearing. Ex: 3.73:1 is taller / higher than 4.56:1
Short gears, AKA low gears = high numerical gearing. Ex: 4.56:1 is shorter / lower than 3.73:1
I agree with everything Dave said. With my manual (Gen II) Tacoma), I have found that 4:56 is the best option. To operate well with bigger tires, more weight, and higher profile, you need to operate higher on the power curve, because the truck requires it. It is not enough to simply match or approximate stock gearing. As it is, I have to shift to 5th on any moderate grade. 6th gear will not sustain 65-70 highway speed, except on mostly flat ground. If I had higher gears, I would virtually never use 6th gear unless I was going down hill. You can get gearing that drops your RPM to 2000, but if 2000 won't move the truck, then you end up down a gear and you have gained nothing. Choosing higher gears also takes a bite out of the truck's crawl ability, which isn't great to begin with. 4.30:1 would be a better choice for 235/85-16, which I ran for a long time. It is both a shorter and lighter tire. All of the modifications that we make to these trucks to make them more capable, also impact fuel economy. There is really no way around it.