it ought not mess with your speedo rating- that is a tone ring thing, or it's a speed sensor in the transmission... the tires affect your overall gear ratio, and they will affect your speedo reading..
you will be better served with 4.10:1 gears, and since you're considering changing, I'd go too low (numerically higher) than too high (numerically lower)...
here's why:
unless you run an overall gear ratio that provides WAY too much leverage for your purpose, such as 5.12:1 or 4.88:1, you're putting load on your engine and wasting energy. Your engine operates in a range of power dictated by power band, which is based off of the camshaft selection in relation to the available air, the lift and duration, and the displacement of the cylinders.. the stroke of the cylinders is of value, too... the displacement determines the proper amount of fuel (catalyst) to be squirted to fire the burn in perfect stioch ratio's of 14.7:1- your sensors monitor that- your foot opens the air and the engine responds accordingly.. when an engine is happily within it's engineered range of power it can easily maintain a 'crossing zero' lambda bounce of less than 3% either way... that is good.. when it is struggling to maintain (or build) power, it is running rich and not producing the power it's capable of... so... what do you do?
you alter the leverage... gears are the leverage... gears in your transmission, and gears in your axles... then, the leverage the diameter of tire figures into the ratio, as said before.
these things are built to meet 'most' expectations customers will put them through... they aren't built to specific purpose, which is up to us... and mod's to support a specific purpose are what we are all about- not just throwing performance parts at it for the sake of bolt on power you can do nothing spectacular with other than having... making the entire rig run in concert and benefit of each other is the ticket..
you're on the right path... gears, providing the leverage in the proper amount, is the easiest way to properly apply the engines energy to the ground..
if you bump to 3.73:1, you'll see an increase in performance and in economy- as measured with a vacuum gauge and demonstration that the engine isn't working as hard to produce the requested task.... if you slap a monitor on it, you'll watch the fuel trim approach zero, after planing off, and start crossing it... STFT's will adjust, making LTFT's adjust, and alterations to your environmental tables will occur, allowing the PCM/ECU to advance spark on a more stable engine, increasing power and economy...
if you bump to 4.10:1, you'll see even more increase...
if you bump to 4.56:1, with those 33's, you'll see a dramatic increase in available power (via leverage), faster accelerations (via leverage) and a dramatic drop in economy (because of wasted energy)... your transmission will appreciate it, though..
three items, and this is mathematics not magic: speed, RPM, overall gear ratio... give me two and I can tell you the third and be dead right every time... the only caveat to this is an unhealthy drive line such as a slipping transmission...
don't fear RPM's... your engine ain't worried about it (up to a point), and your gas usage is more based on engine load (expressed by that vacuum gauge or by monitoring a post exhaust port o2 sensor) more than RPM's... the gov't uses gear ratio's and engine displacement to determine fuel economy in most cases, using the formula i provided, but they do nothing about engine load... it's ALL about engine load.. finding the BALANCE of power produced and leverage to the terra is the game- and you're on it... I just rec the 4.10:1's over anything under it.