The tigers are fine rigs and should definitely be considered. One point to note is that the camper portion of the tiger is _rigidly_ attached to the frame and not based on some type of pivot mount like the earthroamer. Just something to keep in mind, depending on how much frame flex you think you'll encounter while traveling.
Don't own a Tiger (but I am lusting) and I've never owned a vehicle with a pivot frame, but noting how few, if any, Tigers have had frame flex problems over the last 25 years and how many pivot frame efforts have come to catastrophic grief, I'm not sure that this is an automatic show stopper.
Of course, all of the disclaimers must apply - what roads/trails, who designed/excuted, how many examples, etc.
For travel around the US and Latin America, the Tiger appears to hold up very well, with no reports of frame/body damage and minimal damage/wear to cabinets, etc.
If I were seriously worried, I would build myself a "King Tiger" with perhaps a Cognito 4-4" lift and some 32"+ tires and related goodies. Even on an extended cab pickup you ought to be able to get enough rock and roll out of that kind of suspension.
Besides the electronics and the need for low sulphur fuel, the biggest problem with these beasts for severe, third world travel, is the lack of room for fuel, water, and spare parts and recovery junk. But the good news is that most folks don't need much of that and thus can get a camper with 4x4 right off the lot. Not a bad deal.