toyrunner95 made some excellent points there.
have you seen tacodoc's build thread? he's having a bed rack built right now, based on cell4soul's design. take a look around page 25 of the "building an 05 tacoma for expedition travel" thread for a link to the pictures.
as far as your original idea...i like the general idea but not the exo part. how attached are you to your sheetmetal fenders and bedsides? consider this...an expedition vehicle doesnt have to look a certain way, nor does it need to be stock form...it just needs to be reliable, functional, and capable of remaining self-sufficient for a long way over potentially very rough terrain. your exocage is additional metal to protect sheetmetal that doesn't actually serve a particular purpose related to reliability, functionality or capability...the inner bedsides delineate your cargo space, and the channeling and flanges between the inner and outer bedsides provide rigidity. ive always thought of an exocage as turning a buggy inside out...if youll wheel it hard enough to need an exocage, should you be doing it in that truck? and if youre willing to carnage a nice truck like that, why do an exocage when you could put it inside with the same benefit and less wind noise?
so...on to the next part...if youre considering an exocage, i'm gonna assume you have access to a bender, welder, and other handy toys. how about this...go fiberglass. you *will* ditch some weight that can go towards tents and such, and if the going gets really rough, you can pull the fenders and the bedsides--like if youre going on a trail day vs an expedition trip. if you're going fiberglass and you were thinking about an exocage, how about a bed cage to hold the glass in place, dovetail the glass slightly, add a deck for "blank" cargo space, plus permanent mounting locations for gas cans, water, mtn bikes, hi lift, shovel, cooler, drybags and so forth...with an upper deck or hoop to support a rooftop tent no higher than your existing roofline and a sturdy floor that you can stand on similar to cell4soul's rack. if you use larger diameter tube, you can minimize the wall thickness since it's structural, not bash protection, which will keep your center of gravity low. the entire structure will be narrow enough that youll be running difficult trails with the bedsides in place--wide sliders and track width as mentioned previously will keep your doors and bedsides off the rocks--and if you trim the fiberglass fenders, youll have a narrower front end than you would stock, with the same benefits...harder to damage. the cage will replace the structural functionality of box formed by the inner and outer bedsides. also, it's easy to fix fiberglass so it looks like it wasn't hit, and it does flex whereas sheetmetal gets trashed and stays trashed. if you really want to wheel hard when youre not on an expedition trip, the bedcage can be attached to a cab cage and eventually a front clip, all without going exo and with no need to do anything but the bed at first. in addition, you can plan it however you want...30g gas, 20g h20, fuel cell, cooler, bikes, anything you want can have a place since you're designing it and youre not limited to the configuration of the stock sheetmetal.
also, you would not believe how much room there is between the inner and outer bedsides...it's wasted volume. if you glass it, you can use that volume for stuff.
-sean