Got my 255/85r16 Bighorns mounted up. I kept flip-flopping on what suspension to go with so I just mounted my spare up to test fit...
Looked like the only place it would rub was the mudflap, so I took it off.
Then I got the rest mounted up, low and behold... No rubbing whatsoever. Granted, I was only driving around some land I just got, but some spots were flexed all the way to the bump stops.