Should I take it that since I have yet to see this axle design on an overlanding vehicle anywhere in the world that there are few if any practical advantages that would make this design worthwhile for overlanding purposes?
Top loaders are heavy as sin, and with any tires less than 48" the ground clearance isn't anything to write home about. For just about any application short of military or monster trucks, there are generally better choices available.
I'm a huge fan of Mog axles. A) portals, which no only increase ground clearance, but also put less stress on the axle shafts and increase gear ratio options, B) factory air lockers, C) designed to have the housings pressurized for fording, D) CTIS is mechanically simple through the portal hub shafts and E) hydraulic disk brakes.
I'm not so sure about using an ex-U.S. military truck as an RTW type overlander. I seem to recall there is some regulation about not taking them out of the country. If I was going to swap axles onto a non-military truck, I'd opt for Mog axles, which can be had up to (IIRC) 33,600 lb.s rating for a pair and are already designed for single rear tires.
Dana does make some heavy-duty stuff, and they also make portals for many of their axles - but Darrin Fink ran into a problem with Dana axles when doing his FM conversion to 4x4 - IIRC, he couldn't get any that were factory approved for single rears, or he could, but the rear wheels wouldn't work right on the front. Something like that.
I have to say...since I've been looking at this:
http://www.expeditionportal.com/forum/threads/81279-Tatra-T815-my-saga?highlight=t815
I've been falling more and more in love with it.
That whole rigid transaxle down the backbone idea is pretty nifty for a whole lot of reasons, not the least of which is that it eliminates the need for a torsion isolation (3-point/4-point) mounting for the box: