I currently have a late 80's model Yakima 'Space Case' box on my 2004 F250.
I purchased the box from the
Nantahala Outdoor Center in the late 80's while on a white water rafting trip there in NC. I had a 1985 Toyota SR5 Pickup Truck with a camper shell at the time, and installed it in the parking lot. It has been on every truck or SUV I have owned ever since.
I primarily use it for things like sleeping bags, pillows, pads, clothes bags, tents, tarps, etc., and any other soft items that are light weight, need to stay dry, and are not immediately needed when setting up camp. So far, I have not had any problems with it leaking even at 75 mph in the rain, making any noise, or coming open when it's not supposed to. The only things I have had to do to it is, replace the weather stripping and the struts that hold the top up when raised. I also reinforced the strut mounting points at the same time, by adding some aluminum backing plates inside.
Mine opens from the rear, so access can be gained from the rear bumper, the tailgate, or from the sides by using either rear tire to stand on.
I love mine and wouldn't go camping without it!