I've never had a problem with them. At one point in time, I was buying them from gov auctions and reselling, never had a complaint from anyone about them loosening up. If you want to use loctite you can, but be sure to use the light duty Blue stuff and not the Red. The nuts themselves are designed to lock themselves as they are slightly ovaled, but the more often they are removed, the easier they are to loosen. I torque all of mine to 60Ft/lbs, but I've heard others going higher to 70-75.
The only complaint I have with them on a DD are the run-flat inserts. Mine have the low-profile 1 piece rubber run-flats, but there are a few different versions. The military puts a large amount of grease inside the tire to help when the tire blows out or gets shot out and you need to keep driving. Since they are around 30lbs of rubber and the grease isn't necessarily equally distributed, I have a very noticeable vibration at 50-60mph, then it goes away at 65. If I were to cut the mohawk off the runflats and make them just the inner ring, insert, I think it would be greatly improved. Many companies sell nylon and PVC versions of them, but I've seen them crack, so I'm holding out until I can find someone I know with a large enough lathe to turn off the mohawk. Here is a pic of the insert for reference:
They are also making rock rings for the 24 bolts now. These are from a buddy in Oklahoma, but I've seen numerous versions. I'll be welding on the 1st pic version here soon. They are a great option for protecting those studs. Hitting one on a rock or curb is VERY difficult to get off, have to use a very small dremel to cut it out. Since you have access to a machining equipment, you could also make a key to lock a few nuts together or drill out the nuts for safety wire.
I'd be happy to answer any other questions you have. It looks like you have the older Goodyear MT tires on those rims, they aren't very good tires and have a lower load capacity and are nearly impossible to balance. The tires on my truck are the BFG Baja load E that is basically a mud terrain, but there is also a Goodyear MT/R load E that is an all-terrain and very nice on the road. Both balance well and have noticeably better road manners than the MTs you have right now. Here's some old pics of the tread difference.
BFG Baja
Goodyear MT/R
There are also 2 different 24 bolt style wheels, a "paired style" with 12 pairs of nuts, and a "evenly spaced" version where they are even all the way around. I've found that the vast majority of the "evenly spaced" rims have D load range tires and the "paired" version have E rated tires, but ALWAYS double check. Also check the date codes: 4 digit # near the inner bead, first 2 numbers are the week # and last 2 are the year. Really old tires have 3 digit codes, they look good off a rim, but on a rim they are too cracked to be safe IMO.
Sorry for the long post!