Coming from a marine perspective, 24v is fairly common.
Work on 20% maximum discharge of your battery bank, to maximise your battery life. Discharging more than 20% really shortens your battery life.
Wire sizing is worked out by minimising voltage drop, 3% voltage drop is what I aim for, 10% max on non critical systems. Similar to DWH but approached from the other end.
As stated 2x 100amp batteries in series gives you 100amps
Your estimated consumption figures look a littlee high, why would you be running you inverter for so long?
Also consider your charging system from the alternator, and don't forget your solar input.