it would be best to remove the headliner, those bloody metal shards go everywhere, just make sure to make a plastic catch collector under where you are going to catch, it saves a lot of time cleaning up after, a plastic painting floor protecter works fine.
Im sure others will jump in about the cutting of sheet metal, i've just used a jig saw in the past with a metal blade, then file the edges and apply a red oxide paint
While the headliner is off, it makes sense to apply some sound deadener and self adhesive insulation foam, both items make quite a difference
Im interested is how it preforms for you, as i'm interested in using this or the RTX 1000 for my next build as a camper van cooling solution with a larger 24 volt lithium battery pack system.
i'm impressed with my 240ah 12 volt lithium battery in my current build, but i think the next build will incorporate a 300-400ah lithium 24 volt system, to try and run a decent cooling system