The better the insulation (and sealing) of your camper body, the easier it is to maintain the interior temperature when it is occupied and
UNOCCUPIED. (But too much insulation cuts into the small volume you are using as a living space. There is a balance.)
Going skiing/snowshoeing/snowboarding/.. and don't want anything freezing? Going swimming/hiking/... and don't want to return to an oven? Want to return to a comfortable camper when it is cold/raining/roasting/... ? Want to park your vehicle at home for a couple of weeks in the sun/cold/... and easily avoid cooking/freezing/draining/removing/... the contents? Insulation (and sealing) minimize how much energy is needed to maintain the camper within a temperature range that makes you happy.
if you do only a decent job of sealing, you WILL need fresh air when the camper is occupied. My guess is you will do much better than "only a decent job sealing".
I suggest you glue and screw your camper together out of wood, plywood, and rigid insulation. The materials are common, cheap (compared what a composite box would likely cost you), and fairly quick to put together (especially compared to the long build times of some campers). I suspect you are already familiar with the materials.
Because of your rig's capacity, you don't need to be concerned with every pound.
Build your camper and get out and use it. Too many DIY boat-builders spend years building their boats without using them, and some DIY camper builders do the same.
Build your camper as a solid, road/offroad-worthy, sealed, insulated, ventilated, heated and cooled tiny-home you can enjoy traveling in for the 5 years (or more) that you mentioned.
Keep your costs and your build-time down, and you can always remove your camper, sell it as a tiny-home, and mount your new and improved Mark II model.