Even using a manual switch, like a Perko or a Blue Sea, you NEED to have fusing, or breakers... Because you have a battery at each end of the cable, you need a fuse or a breaker ("protection" from here on) at each end. If you do not, and a short occurs in the middle of the cable, having protection at only one end still leaves the other battery connected to the short, and it will continue to short out. Having protection at both ends, if the cable shorts in the middle, both fuses will blow or breakers will open, and the batteries are now protected from the short.
Protection should be within 18" of the battery at each end. I say 18" because within that distance, it is very unlikely there can be a short between the protection and the battery. My personal preference is a cooper bussmann breaker, it should be at least 175 amp if you ever intend to use the aux battery to "jump start" the main battery.
Example, using text crudely
[ALTERNATOR]-----------[MAIN BATTERY]-----[175A BREAKER]--------------[MANUAL SWITCH OR ACR]--------------[175 AMP BREAKER]-----[AUX BATTERY]
This "diagram" shows the manual switch or ACR directly in the middle of the circuit, because it can be there, or anywhere between the breakers or fuses.
The absolute beauty if this scenario is you can put a manual switch in there now, and at any time later, upgrade to an ACR, or a solenoid or a CTEK. Anything but a diode isolator

.