From your perspective it may be no big deal running a spool, or by extension a welded diff. The differences between a spool and a Detroit or other automatic locker are night and day in terms of driving and the effects on the vehicle overall, and on the life of your tires.
With a Detroit or automatic locker, as long as you are not driving under positive throttle around corners, the locker will coast. You will hear this as a clicking or knocking noise, but it is harmless and it is the way they work. At least the rear tires will differentiate while turning and save some rubber.
With a spool, both rear tires will be forever locked together and can not under any circumstances do anything other than turn at the same rate. Since the ONLY time a vehicles' tires turn at the same rate is while going dead straight, your spooled axle will be scrubbing tires any time you are not going perfectly straight down the road. This is assuming your tires are aired the same on both sides. Unequal air will cause tire scrubbing even when driving straight.
Constant tire scrubbing while driving on hard surfaces will cause accelerated tire wear, excessive tire heat, and wear and tear on drive line and steering components. It tends to wind up your axle shafts, and constant loading and unloading of the shafts is not a good thing for shafts or for splines.
It also causes a degrading in fuel economy, takes more power to simply drive down the street, stresses the transmission by increasing the load required to drive forward, increases turning circle, often dramatically, and after a very short period of time, gets to be a pain in the butt.
If the choices were to drive open, or weld or spool the rear because no locker is available, I would drive open. Welding and spools are for drag racers and trailer queens.