YMMV. but a good rule is anything you do to make your rig it taller, iincrease rolling resistance/ground clearence, impact aerodynamics will at a minimum, cost you 1 mpg each at steady state 60-65 mph.
Bigger tires +1 size up and 1 size wider (I assume the tire will be slightly heavier): -1 mpg (go mondo here, and expect more loss)
Raise 2-4 inches? -1mpg (go mondo here, and expect more loss)
Remove airdam, cut bumpers/add aggressive bumper for better approach or big, unconcealed winch brush guard? -1 mpg
This is exponential, so the faster you go, the worse the sum of the above will be. With big trucks/rigs, if you never go above 40-50 mph, you might see only -1 mpg at steady state.
At slow/stop go speeds, heavy weight eats MPG.
Once up to speed, rolling/wind resistance eat your MPG.
Again, YMMV