I've been running these on my 2012 F250, in a 37 1250 17 size.
They have been on the truck for just over 20,000 miles, and I do expect to see another 10-15K out of them.
I tow almost daily, averaging around 6000 lbs in a 14' enclosed trailer for work. I do construction work, so muddy, steep, rutted job sites are common place for me.
They have worn evenly, and require very little (if any) weight to balance.
Dry pavement, they are very nice. Not too loud, but a slight hum (it is a mud tire after all)
Wet pavement, they tend to be a little loose for my liking, but not so much that I feel unsafe.
Mud/rocks, just awesome. They seem to find grip where there really shouldn't be anY.
Snow (used up to 8" deep) they were excellent at cleaning out and keeping my heavy truck moving.
Icy roads, they are ok. But again, it's a mud tire, so you will need to be careful.
Now, to clarify all this. I live in the western end of North Carolina. Lots of curvy roads and elevation changes. The roads here are mainly made with crushed granite which is naturally abrasive and slick when wet. I do feel that these tires (and any tire really) wear faster in this area because of how the roads are. I used to live in Central Florida, which is flat, and roads are either concrete (sandstone) or blacktop, which is a far more forgiving surface than what's used up here. Tires on my trucks in FL lasted far longer than they do up here. I had a set of 40" GoodYear Wrangler MT/R's on my 2005 Super Duty, and had nearly 60,000 miles on them with a good 7-8/32 of tread left on them when I sold it. I domt see any tires really lasting very long up here. It's something that needs to be considered when looking at tire reviews.
Hope this all helps.