Yay!!!, i just swapped my GMC (2007 sierra classic 6.0L) from a 4L80E auto to an NV4500. My NV4500 came out of a cab and chassis truck and is definitly a truck transmission in the sense that it shift slow due to the extremely large and heavy gear sets (takes a while to syncronize the gears). Because of this I believe the NV4500 to be one of the toughest 5 speed transmissions in this class of transmission.
Make sure if you do a fluid swap you use GL4 rates oil, castrol syn torq i believe is the stuff, a quick google search will put you on the right path, there is the AC Delco stuff, The Castrol Stuff, and the Mopar stuff. From what I understand its all the same oil, just badged differently. Also its crazy expensive, i believe I got the AC delco for about 21 dollars a quart and put in 4.5 quarts (.5 overfilled).
Have fun with the truck should be solid!!!
Cheers,
Edit, also my transmission with respect to tougher shifting is the early 6.34 1st gear ratio, yours will be the 5.61, first year they swapped to the higher 1st gear ratio. I believe my first and reverse is not syncro'd, it shows, have to be stopped to get into gear, yours will be syncro'd, should shift a bit smoother through all gears.