Desert Dude:
I thought of something that is related to your rotation/balance question; tire pressures.
I don’t run lots of air-pressure, even on my F350. It has never seemed to cost me MPG or tire wear, and I believe it assist with traction. handling and ride quality. I don’t run low/under-inflated tires, merely appropriate PSI for the load. Light loads means less PSI, more weight requires more PSI. On my lighter vehicles (Jeep/Toyota) it is easy to pick one on-highway PSI that works on the car and stick with it unless you like to play with things like I do.
My practice.
An LT255/85R16D and LT265/75R16D both are rated to carry 3,000-lbs per tire in a SRW (single rear wheel) application at 65-PSI. Since few of us are driving 4x4s weighing 12,000-lbs (6k on each axle) this is too much pressure. The tires will be overly firm, hurting both ride quality and traction.
At 35-PSI the 255/85 is rated for 1920-lbs and the 265/75 is good for 1910-lbs. That is close enough to not matter and I will use the 255/85 capacity as that is the size I prefer. At 35-PSI there is still much more capacity than is usually needed, 3,840-lbs! I don’t think it is bad to simply run 35-psi, but I don’t think people need to go above that for better MPG. The tires are already pretty pumped-up unless the truck has 3,840-lbs on each axle.
The inflation charts I have seen don’t go below 35-psi and maybe that is because there are no standards for less psi, but I don’t accept the notion that the tires are not safe to be run at lower than 35-psi if the load is light for a given tire. An example of this is on my ‘06 4Runner. According to Toyota and the sticker on the door jam the stock P265/70R16 tires were rated to carry 3,295-lbs at 32-psi on the rear axle. The front axle is only rated for 2710-lbs and Toyota suggests the same 32-PSI (KISS I believe). These are the gross axle weight ratings (GAWR) for the vehicle. If the axles are carrying less weight, and they are even after all my modifications, they don’t really even need the full 32-psi. Remember this is after the Ford Explorer/Firestone mess and I’m confident there is extra capacity built into this 32-psi number for Toyota’s legal department. Why 32 instead of 35, because 35 is overkill and overall ride, handling, and traction will be better with and appropriate, lower psi.
This doesn't mean that I run 25-psi on the highway, but I have experimented with pressures below 30-psi. My current air pressure for my 4Runner is 32, just because that’s what Toyota recommends, it rides and drives well and the TPMS sensors don’t put a light on the dash. I have experimented with less, and just yesterday drove a short distance with 35, which I promptly bled out upon returning home as it didn’t feel right. I’m not finished experimenting ☺