I did the same setup in my Tacoma about 3 years back. The write up is here:
https://www.tacomaworld.com/threads/12v-bed-outlet-install-write-up.378833/
I ran 10 gauge wire to a fuse block in the bed with a 50 qt ARB fridge. Worked like a champ for 3 years (i've since upgrade to a Ram 1500 and about the do the same think again). On the tacoma it was simple as it had a composite bed. I'm thinking for the Ram i'll put all the electronics into a metal box and mount the box to the bed wall.
Only change I would have made would be putting in 3x 12v outlets instead of the gauge/usb/12v combo.
The fuse block was nice. I later added some LED backup lights (see:
https://www.tacomaworld.com/threads/12v-bed-outlet-install-write-up.378833/#post-11718310) and was able to tie into the existing power.
Just be sure to fuse everything properly (I think I had 30 amp on the wire at the battery, 15 amp for the 12v and 3 amp for backup lights and USB)