Hmmm, 22v seems low for an MPPT, the whole point of them is to be good with higher voltages. But I suppose if it's a cheapie designed for a 12v system.
Still if it says 22v you have to assume that any more than that will blow it up, regardless of what the label is on the panel. So as Voc is the highest the panel can produce, you have to assume that voltage will appear across the regulator one day.
If for example you were to connect the panel to the controller before the batteries, that would almost certainly have no load so Voc will be placed across the regulator, not good. You can say "ok I'll never do that, I'll always connect the battery first", but if a battery lead comes off or you forget in 2 years and take one off for maintenance, poof, there goes the regulator (maybe, maybe not, depends on conditions at the time and how robust it's been designed).
So the short answer is that IMO that regulator is possibly not suitable for panels with a Voc > 22V, or is it the other way around?