I singled mine out in stages.
Starting with keeping the dually hubs and running h1 rims which have 7" backspacing. This required 2.5" spacers on the rear to get the tires out enough to clear the box wheel wells.
Recently I fully singled it out by getting some "regular" 17" rims. Loosing the rear spacers and swapping the front DRW hubs for SRW hubs. I downsized tires to 35" 12.5 r17.
Much like Ozrockrat did except I did not go to 19.5 rims and tires, because we have a lot of sand here and I wanted to retain the ability to air down a bit.
For me I think this is the correct combo.
Most of these trucks spend a good deal of time on the road. This combo is very street able, but retains the ability to air down for soft sand. I have not had the new tires in snow, but imagine they should work well.
Keep in mind mine is not as heavy as the wide box long wheelbase ambos out there.
Some of those may be pushing the limits weight wise singled out and loaded. At least with standard rims and tires. Ozrockrat got around this by running a heavier truck tire and rim to handle the extra weight.
So there are many things to consider and all options are a compromise in one way or another. You just have to find the compromise that best fits your needs.
Here are the hubs I swapped and my current setup.
